Description
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Etizolam is a thienodiazepine derivative that acts on the benzodiazepine receptor, making it a benzodiazepine. Etizolam suppliers, buy etizolam powder, etizolam powder suppliers, etizolam for sale, etizolam powder wholesale from China.
Legit Cannabinoids sells it for the purpose of research on the internet. The FDA has not approved Etizolam for medicinal use. Still, our online store helps you buy Etizolam online without any hassle. Furthermore, Etizolam is only available as a pharmaceutical substance in a few countries.
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The Etizolam powder for sale at our online store helps you in the treatment of generalized anxiety disorder with depression, insomnia, and panic disorder.
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Etizolam increases GABAergic transmission and enhances GABA-induced Cl- currents by acting as a complete agonist at GABA-A receptors. It is thought to bind to the benzodiazepine binding site, which is positioned across the alpha-gamma subunit interface. According to reports, benzodiazepines only bind to receptors that contain the gamma 2 and alpha 1/2/3/5 subunits.
Etizolam sedative effects are mediated by alpha-1 receptors, and the anxiolytic action is mediated by alpha-2 and alpha-3 subunit-containing receptors. With the alpha 1 beta 2 gamma 2S subunit combination, Etizolam has high efficacy and affinity for the GABA-A receptor.
Etizolam increases GABA transmission by promoting the opening of GABA-induced chloride channels by binding to the receptor’s regulatory region. Etizolam is a particular PAFR antagonist. With an IC50 of 22nM, it inhibits PAF-induced platelet aggregation by blocking PAF binding to receptors on platelet surfaces.
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Etizolam is a central nervous system depressant with anxiolytic, anticonvulsant, sedative-hypnotic, and muscle relaxant properties. As an agonist, it increases inhibitory GABAergic transmission throughout the central nervous system by binding to the benzodiazepine region of the GABA-A receptor. According to studies, Etizolam appears to have 6 to 10 times the potency of diazepam in mediating its pharmacological activities.
Pharmacodynamics
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