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In veterinary medicine, the opioid analgesic carfentanil or carfentanyl, marketed under the trade name Wildnil, is used to anesthetize big animals such as elephants and bears. Tranquilizer needles are the most common method of administering them in this setting.

Opioid receptors have also been mapped using Carfentanil in humans. Illegal users often inject, insufflate, or inhale the substance as a form of abuse. At Legit Cannabinoids, we have Carfentanil powder for sale available. Order yours now!

Effects of Carfentanil

Its benefits and adverse effects in humans are similar to those of other opioids, including euphoria, relaxation, pain relief, and pupil constriction. These are all symptoms of overdose, along with slow heart rate, low blood pressure, reduced body temperature, and loss of consciousness.

The opioid antagonist’s naloxone and naltrexone can reverse Carfentanil’s effects, including overdose; however, greater or repeated doses than normal may be required compared to other opioids.

Carfentanil is a structural counterpart of fentanyl, a synthetic opioid analgesic used to treat severe pain. It is a powerful and highly specific agonist of the -opioid receptor, which is why it is so effective.

A team of Janssen Pharmaceutica scientists, led by Paul Janssen, originally synthesized Carfentanil in 1974. In 1986, it was first used in veterinary medicine. Carfentanil is regulated in the majority of countries.


When you buy Carfentanil online USA, there are primarily three uses. They are:

Veterinary use

Carfentanil was initially introduced in 1986 under the trade name “Wildnil” as a tranquilizer for big creatures including hippos, rhinos, and elephants because of its high therapeutic index. Wildnil’s commercial manufacture halted in 2003; the medicine is currently only accessible in compounded form.

Clinical use

For human positron emission tomography imaging of the -opioid receptor, low dosages of Carfentanil have been used as a radiotracer.


μ-opioid receptors are specifically activated by Carfentanil, which functions as a potent agonist. They found that it had an affinity (Ki) of just 0.051 nM with respect to opioid receptors in the brain of a rat, as well as affinity (Ki) values of 4.7 and 13 for opioid receptors in the rat. It was shown that Carfentanil has a selectivity for the -opioid receptor of 90 and 250 times over the μ-opioid receptor.

With human proteins, the affinities for the -opioid receptor were 0.024 nM, whereas those for the -opioid and -opioid receptors were 3.3 and 43 nM, respectively, indicating selectivity of 1,800 times for the -opioid receptor over the -opioid receptor.

There is some evidence that buy Carfentanil online has a greater affinity for the 1-opioid receptor than the 2-opioid receptor. In animal trials, Carfentanil has analgesic strength 10,000 times more than morphine, 4,000 times greater than heroin, and 20 to 100 times greater than fentanyl.

Because of the great potency of Carfentanil, larger dosages of -opioid receptor antagonists such as naloxone and naltrexone are often required in humans to counteract the drug’s effects.


Faster acting than fentanyl, Carfentanil is a lipophilic drug that may rapidly pass the blood-brain barrier. An intravenous bolus of 1.34 g (19 ng/kg) has an elimination half-life in humans of 42 to 51 minutes.

The half-lives of Carfentanil and its metabolite nor carfentanil were determined to be 5.7 hours and 11.8 hours, respectively, in a case study of recreational exposure.

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